双光子显微镜

型号：Neurolabware

品牌：Neurolabware

产品名称：在体共振扫描双光子显微镜

典型应用：神经生物学、细胞生物学、代谢组学、信号传导等生命医学领域的在体或厚组织的三维成像。

Resonant Scanning Two-Photon Microscope optimized for in vivo imaging

Neurolabware是目前科研领域内性能最优秀的在体共振扫描双光子显微镜平台。2011年由物理学家Adrian Cheng博士, 神经生物学家Josh Trachtenberg教授和双光子显微镜专家Jennifer Park博士共同设计，已广泛应用于生物医学科研领域，在美国和欧洲等国家有四十多个顶级实验室先后采购和使用，相当数量的研究成果和论文已发表在Neuron，Neuroscience等核心期刊上。

产品特点

1. 通过实时双向30Hz扫描实时成像

2. 触屏式四轴控制，研究人员可在熟悉的环境下熟练操作

3. 实时防抖成像

4. 在线数据分析系统

5. 快速Z扫描，同时浏览多层数据

6. 良好的兼容性与扩展性，支持与Matlab、Python等的数据交换。

7. 精确的时间戳

引用案例：

Burgess, CR*, Ramesh, RN*, Sugden, AU, Levandowski, KM, Minnig, MA, Fenselau, HF, Lowell, BB, and Andermann, ML. Hunger-dependent enhancement of food cue responses in mouse postrhinal cortex and lateral amygdala. Neuron, in press. (* co-first author).

Economo, Michael N., Kyle R. Hansen, and Matt Wachowiak. “Control of Mitral/Tufted Cell Output by Selective Inhibition among Olfactory Bulb Glomeruli.”Neuron 91, no. 2 (July 20, 2016): 397–411. doi:10.1016/j.neuron.2016.06.001.

Katrien, Mols, Prodanov Dimiter, and Bonin Vincent. “Scale-Space Based Segmentation of Cells in Functional Two-Photon in Vivo Images.”Frontiers in Neuroinformatics 7 (2013). doi:10.3389/conf.fninf.2013.10.00033.

Mineault, Patrick J., Elaine Tring, Joshua T. Trachtenberg, and Dario L. Ringach. “Enhanced Spatial Resolution During Locomotion and Heightened Attention in Mouse Primary Visual Cortex.”The Journal of Neuroscience 36, no. 24 (June 15, 2016): 6382–92. doi:10.1523/JNEUROSCI.0430-16.2016.

Nelson, Anders, and Richard Mooney. “The Basal Forebrain and Motor Cortex Provide Convergent yet Distinct Movement-Related Inputs to the Auditory Cortex.”Neuron 90, no. 3 (May 4, 2016): 635–48. doi:10.1016/j.neuron.2016.03.031.

Ringach, Dario L., Patrick J. Mineault, Elaine Tring, Nicholas D. Olivas, Pablo Garcia-Junco-Clemente, and Joshua T. Trachtenberg. “Spatial Clustering of Tuning in Mouse Primary Visual Cortex.”Nature Communications 7 (August 2, 2016): 12270. doi:10.1038/ncomms12270.